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A fascinating detective tale and moving memoir of loss of life and deceit. When Dr William Macbeth poisoned two of his sons in 1927, his better half and sister hid the murders in the intensely private realm of family secrets. Like the famous poisoner Dr Crippen, Macbeth behaved as though he were immune to outcomes; unlike Crippen, he prevented detection and consequence...or have he? As time handed down, the storyplot of Dr William Macbeth, well-dressed poisoner, haunted and divided his descendants. Macbeth's granddaughter Gail Bell, who grew up with the storyplot, spent 10 years reading the literature of poisoning in order to understand Macbeth's life. A chemist herself, she listened for echoes in the great instances of the 19th and 20th ages, in myths, fiction and poison lore. This complex tale, with a moving twist at the end, is a book about family guilt and secrets, and also an exploration of the type of loss of life itself as Bell becomes to her grandfather's poisonous predecessors, from Cleopatra, Madame Bovary and Napoleon to prolific serial killer, Harold Shipman.