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In Brooklyn in 1899, Dr. Noah Whitestone is called urgently to his rich neighbor's house to take care of a five-year-old son with a shocking group of symptoms. When the child dies out of the blue later that evening, Noah is accused by the boy's regular doctor - the powerful and politically linked Dr. Arnold Frias - of prescribing a lethal medication dosage of laudanum. To show his innocence, Noah must check out the murder - for this must be murder - and confront the man he is persuaded is the true killer. His research leads him to a reporter for a muckraking magazine and a beautiful radical editor who are convinced that a top secret experimental drug from Germany has brought on the loss of life of at least five local children. By diplomas, Noah is drawn into an unhealthy world of drugs, crooks, and politics, which threatens not only his job, but also his life.